Irena Sailer received her dental education and Dr. med. dent. degree from the Faculty of Medicine, University of Tübingen, Germany in 1997/ 1998. In 2003 Dr. Sailer received an Assistant Professorship at the Clinic of Fixed and Removable Prosthodontics and Dental Material Sciences in Zurich. Since September 2013 she is the Head of the Division of Fixed Prosthodontics and Biomaterials at the University of Geneva. Irena Sailer is a Specialist for Prosthodontics (Swiss Society for Reconstructive Dentistry) and holds a specialization degree for Dental Implantology (WBA) of the Swiss Society for Dentistry. 

Since 2019 Irena Sailer is an Honorary Professor at the University of Aarhus, Denmark. Since 2009, she served as Adjunct Associate Professor at the Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, USA until October 2024, and holds a position as Senior Associate Dean for Digital transformation at Columbia University College of Dental Medicine as of October 2024.

She is the President Elect of the EAO (European Association for Osseointegration), and the President of the EAED (European Academy of Esthetic Dentistry). She is also an Active Fellow of the GNYAP (Greater New York Academy of Prosthodontics), and a past Member of the Board of Directors of the SSRD (Swiss Society of Reconstructive Dentistry) and of the Swiss Leadership Team of the ITI (International Team for Implantology). 

Since 2019 Irena Sailer is the Editor-in-Chief of the International Journal of Prosthodontics and a member of ICP.