CAD/CAM Digital & Oral Facial Aesthetics 37th Int’l Dental ConfEx

Abstract

Treatment of Periodontitis determine significant reduction of indicators of progression of the diseases. Nevertheless, beneficial effect of therapy are extended far beyond the boundaries of the oral cavity. In particular, literature has identified important changes,  both short and medium to long-term, of bio-markers of cardio-vascular health such as inflammatory bio-markers, endothelial function, glycaemic levels and lipids function. Immediately after periodontal instrumentation a relevant perturbation of the systemic inflammation and endothelial dysfunction has been observed through a sharp and abrupt increase of inflammatory markers. Nevertheless, when periodontal inflammation subsides beneficial systemic effects are seldom noted. Systemic inflammation decreases as observed by reduction of the circulatory level inflammatory markers. Metabolic markers also show improvements as witnessed by small yet significant changes in lipid markers and, in subjects affected by diabetes, by a significant reduction on the level of glycated haemoglobin. Moreover, study on the endothelial function also indicates a beneficial effect of periodontal treatment. Thus, on the basis of the available evidence, periodontal treatment appear to determine beneficial effects on bio-markers of cardio-metabolic-vascular health and quality of life. The impact on the overall well-being of such effects is yet to be determined.