In this Review due to expanding availability of SDF we discuss the effectiveness, indications for appliance and its disadvantages. We will focus on SDF usage in pediatric dentistry. Literature searches were conducted in PubMed/MEDLINE, Embase, Cochrane Central Register of Controlled Trials, to identify studies that are related to our topic “Silver Diamine Fluoride in Pediatric Dentistry” that were published up to May 2018. It is mentioned in the literary works that the most efficient, simplest, and least expensive decays preventive representatives are silver nitrate (which eliminates the causative bacteria) and fluoride (which makes the teeth much less soluble to bacterial acids)). The creation of a silver nitrate fluoride construct -silver diamine fluoride (SDF) -combines these two preventative representatives. SDF is thought to arrest and protect against decay progression by killing the original bacteria, depositing a layer of safety silver phosphate that resists additional decay, and transforming the even more acid soluble hydroxyapatite to the much less soluble fluorapatite.